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Erectile dysfunction is a common issue that impacts many people. Find out more about Medicare plans and Viagra protection.i.d.) resulted within a 63% reduce of sildenafil AUC in addition to a 55% reduce in sildenafil Cmax . Concomitant administration of robust CYP3A4 inducers, like rifampin, is expected to result in higher decreases in plasma amoun
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Sildenafil can be a potent and selective inhibitor of cGMP-specific phosphodiesterase form 5 (PDE5), that's responsible for degradation of cGMP during the corpus cavernosum. The molecular composition of sildenafil is analogous to that of cGMP and acts as a competitive binding agent of PDE5 within the corpus cavernosum, leading to more cGMP and grea